The global life sciences and biopharmaceutical industry is evolving at an unprecedented pace. Breakthroughs in cutting-edge technologies and global R&D collaboration have become the key drivers of industry growth. As technology continues to advance, the global market maintains strong growth momentum. Many companies are building global R&D networks with research centers across multiple countries and regions. However, multinational and multi-entity operations also bring increasing challenges in financial and tax management, audit compliance, and corporate governance.
Sirnaomics Ltd. (HKEX: 2257), a Hong Kong-listed company specializing in innovative RNA therapeutics, also faced operational challenges such as fragmented financial data across regions and inefficient manual financial reporting. To address these global management challenges, Sirnaomics partnered with Oracle NetSuite and Melin to build a lightweight, multilingual, and modular integrated business and finance platform.
About Sirnaomics
Sirnaomics Ltd. (HKEX: 2257) is a globally recognized biopharmaceutical company dedicated to unlocking the full potential of RNA-targeted therapeutics.
Founded in 2007, the company was established with the mission of overcoming one of the key technological bottlenecks in the RNA field—efficient drug delivery. Leveraging its two proprietary core technology platforms, Peptide Nanoparticle (PNP) and GalAhead™, Sirnaomics has achieved precise liver-targeted delivery and continues to expand into high-value extrahepatic therapeutic areas, including oncology, cardiometabolic diseases, and high-potential medical aesthetics.
Sirnaomics overcomes the limitations of traditional protein-targeted therapeutics by directly targeting RNA, significantly expanding the range of druggable targets and treatment possibilities for difficult-to-treat diseases. Through this next-generation technology platform, the company has developed highly specific, long-lasting, and customized RNA interference (RNAi) therapies that surpass the limitations of first-generation oligonucleotide therapeutics. Today, multiple pipeline candidates have entered clinical development and are steadily progressing toward commercialization.
Sirnaomics is more than a drug discovery company. It is redefining the future of precision RNA medicine through continuous innovation and scalable value creation, bringing transformative therapies to patients worldwide.
Multi-Regional Business Operations
Optimizing Global Management
Sirnaomics conducts R&D operations across Mainland China, Hong Kong , and the United States. Previously, the financial systems in these three regions operated independently, making it difficult to consolidate group financial statements and standardize accounting across entities. Differences in reporting standards frequently occurred during consolidation, while various reports relied heavily on manual Excel processing, resulting in lengthy reporting cycles. Meanwhile, internal control processes such as procurement and expense approvals lacked complete online records, making document traceability difficult.
To address these operational challenges, Sirnaomics sought a digital management platform capable of supporting synchronized multi-region deployment, flexible module selection, and multilingual functionality. After multiple rounds of competitive research and evaluation, Oracle NetSuite stood out with its core advantages, including multilingual support, multi-currency capabilities, lightweight architecture, and flexible scalability.
Multilingual Support for Global Teams
Oracle NetSuite supports multiple languages, enabling teams in Mainland China, Hong Kong SAR, and the United States to work seamlessly on the same platform while meeting local user requirements.
Lightweight and Highly Scalable
Oracle NetSuite allows modules to be selected and deployed based on business needs. Sirnaomics configured only the essential modules required for its current business operations, avoiding unnecessary functionality while maintaining flexibility for future expansion.
During the implementation phase, Melin, an Oracle NetSuite Five-Star Partner, was responsible for the complete project lifecycle, including system deployment, go-live configuration, and long-term operation and maintenance. Having served numerous biopharmaceutical companies, Melin possesses extensive expertise in the financial accounting and procurement approval processes unique to innovative pharmaceutical enterprises.
At the beginning of the project, the implementation team designed a tailored solution based on Sirnaomics’ pipeline R&D model and multinational multi-entity operations. From requirements analysis and process configuration to system testing and user training, the entire implementation followed a closed-loop approach. Within just four months, followed by a one-month post-go-live optimization period, the system was successfully deployed simultaneously across Mainland China, Hong Kong SAR, and the United States.
Unified Management Across Multiple Regions
Comprehensive Upgrades in Financial Management and Internal Controls
Following the implementation of Oracle NetSuite, Sirnaomics successfully eliminated the challenges associated with fragmented multi-regional financial management, achieving significant improvements in financial efficiency, internal control compliance, operational flexibility, and global data consistency.
Significantly Improved Consolidation Efficiency and Shorter Financial Closing Cycles
Previously, all financial data was manually consolidated in Excel, requiring seven days to prepare a complete set of consolidated financial statements. After adopting Oracle NetSuite, the system generates consolidated financial reports automatically with minimal manual review, reducing the financial closing cycle to just two to three days.
End-to-End Traceability and Stronger Internal Controls
Procurement approvals, expense journals, and payment processes have all been migrated to digital workflows. Every business transaction and every approval action is recorded with a complete audit trail, allowing the corresponding approver and process step to be traced at any time. This has significantly improved the transparency and standardization of the Group’s internal control system.
Flexible Modular Deployment for Every Stage of Growth
Sirnaomics can flexibly configure system modules according to its business needs. At the current stage, only essential R&D-related modules have been deployed, effectively controlling digital transformation costs. As the company’s core pipelines enter commercial manufacturing, additional sales and manufacturing modules can be implemented as required.
One Global Data Source Supporting Unified Decision-Making
Teams in Mainland China, Hong Kong SAR, and the United States all use the same system for financial management, eliminating the data silos created by multiple local software systems. Management can access standardized, real-time global operational data at any time, providing a reliable foundation for R&D cost management and global business decision-making.
Sirnaomics’ digital transformation demonstrates that Oracle NetSuite, as a cloud-native ERP built for global businesses, provides a comprehensive solution for the challenges faced by multinational pharmaceutical companies, including multi-entity operations, integrated business and financial management, and compliance governance.
Looking ahead, Oracle NetSuite will continue working with partners such as Melin to leverage its AI-powered integrated business management suite, helping more multinational innovative pharmaceutical companies gain deeper business insights while building global digital solutions that support the entire R&D lifecycle and accelerate global business growth.
All data presented in this article is provided by the customer.
About Melin
Melin is an Oracle NetSuite Five-Star Partner. Since Oracle NetSuite entered the Chinese market in 2017, Melin has been among the first consulting and implementation partners specializing in Oracle NetSuite in China.
Since its establishment, Melin has delivered professional NetSuite services to more than 100 customers across China and overseas, serving industries including biopharmaceuticals, medical devices, fintech, manufacturing, professional services, and wholesale distribution. Its international customer base spans the United States, Canada, Australia, Singapore, Japan, and many other countries and regions.
We deeply integrate the Oracle NetSuite ERP platform with the latest AI technologies, enabling customers to respond confidently to market changes through flexible innovation and global expansion while achieving new milestones in digital transformation.
At the same time, we remain committed to a customer-centric service philosophy. Backed by exceptional project delivery capabilities, we provide customers with dependable solutions they can truly trust.